别名: (+)-荷包牡丹碱;比扣扣灵;毕枯枯灵;山乌龟碱
英文名:(+)-Bicuculline,d-Bicuculline
分子式:C20H17NO6
分子量: 367.35
外观: elongated plates from chloroform-menthanol or pale yellow crystalline powder
溶解性: soluble in benzene, chloroform, ethyl acetate. Sparingly soluble in alcohol and ether
纯度: >99%
CAS No: 485-49-4
Long Term Storage:-20°C
比扣扣灵也称毕枯枯灵,别名右旋荷包牡丹碱。从紫菫属植物中分离纯化⊙,GABA A受□体竞争性拮抗剂,是研究GABA能突触传递的重要工具.
Product Literature References:
Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production: Sarah E. Hoey, et al.; J. Neurosci. 29, 4442 (2009), Abstract;
Convulsant bicuculline modifies CNS muscarinic receptor affinity: P.G. Schneider and G. Rodriguez de Lores Arnaiz; BMC Neurosci. 7, 32 (2006), Abstract; Full Text
Cannabinoid suppressed bicuculline-induced convulsion without respiratory depression in the brainstem-spinal cord preparation from newborn rats: S. Koda, et al.; Biomed. Res. 26, 241 (2005), Abstract; Full Text
(产品仅适用于科学实验,不得用于其他ㄨ目的).