别名: (6R,8S)-6,8-二氢-6-[(5S)-5,6,7,8-四氢-6-甲基-1,3-二氧杂环戊并[4,5-g]异喹啉-5-基]呋喃并[3,4-e]-1,3-苯并二氧杂环戊烯-8-醇 英文名:(+)-Egenine
Alternative Name:6-(6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,8-dihydrofuro[3,4-E][1,3]benzodioxol-8-ol, (+)-Decumbensine
分子式:C20H19NO6
分子量: 369.37
外观: White to off-white crystalline solid
溶解性: Soluble in ethyl acetate or chloroform; sparingly soluble in 100% ethanol or ether; practically insoluble in water
纯度: >99%
CAS No: 6883-44-9 Biological Activity:
First phthalideisoquinoline hemiacetal from a natural source. Inhibits Ca2+ currents and contractile responses in vitro.Egenine是生物碱类化合物,荷包牡丹碱的生物前体,有收缩心房肌的□作用。纯度98%以上,检测方法HPLC,用于医药研究及含量测定,现货
Product Literature References
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1-Magnesiotetrahydroisoquinolyloxazolines as chiral nucleophiles in stereoselective additions to aldehydes: Auxiliary optimization, asymmetric synthesis of (+)-corlumine, (+)-bicuculline, (+)-egenine, and (+)-corytensine, and preliminary (13)C NMR studies: R.E. Gawley & P. Zhang; J. Org. Chem. 61, 8103 (1996), Abstract;
β-Phenylethylamines and the isoquinoline alkaloids: K.W. Bentley; Natural Prod. Rep. 11, 555 (1994), (Review),
Synthesis of phthalide isoquinoline alkaloides (-)-egenine, (-)-corytensine, and (-)-bicuculline by asymmetric carbonyl addition of chiral dipole-stabilized organometallics: K.S. Rein & R.E. Gawley; J. Org. Chem. 56, 1564 (1991),
Synthesis of (-)-egenine (decumbensine) by asymmetric carbonyl addition: K.S. Rein & R.E. Gawley; Tetrahedron Lett. 31, 3711 (1990),
Egenine: A possible intermediate in phthalideisoquinoline biogenesis: B. Gotzler, et al.; Tetrahedron 39, 577 (1983),