A 769662
Chemical Name:6,7-Dihydro-4-hydroxy-3-(2-hydroxy[1,1-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
M.Wt:360.39
Formula:C20H12N2O3S
Solubility:Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:>99%
Storage:Store at +4°C
CAS No: 844499-71-4
Biological Activity:
Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo.
