产品说明:
Intended Use
The SeroFIA™ C.psittaci is a semi-quantitative immunofluorescence assay for the differential determination of C.psittaci specific IgG, IgA and IgM antibodies in a single human serum sample.
For In Vitro Diagnostic Use.
Introduction
Chlamydia, a highly specialized Gram-negative bacteria, is composed of four species: C. trachomatis, C. pneumoniae (TWAR), C. psittaci and C. pecorum. C. trachomatis includes 15 serotypes sharing immunogenic epitopes at various degrees. C.trachomatis is a major sexually
transmitted disease and is associated with nongonococcal urethritis (NGU) and epididymitis in men, cervicitis, urethritis and pelvic inflammatory disease in women, Reiters syndrome
in HLA-B27 haplotype individuals and neonatal conjunctivitis and pneumonia in the newborn (2-6).
C. pneumoniae is an important respiratory pathogen in humans and causes up to 10% of community-acquired pneumonia cases. It has been associated with acute respiratory diseases,
pneumonia, asthma, bronchitis, pharyngitis, acute chest syndrome of sickle cell disease, coronary heart disease, and Guillain-Barre syndrome (7-9).
C.psittaci infects a diverse range of host species from molluscs to birds to mammals and also causes severe pneumonia. Serological testing is routinely used for diagnosing chlamydial
infections. They serve as a non-invasive tool in identification of both distal and chronic chlamydial infections (10, 11), where direct detection methods are rarely efficient. Furthermore, the presence of certain antibody types may also indicate the state of the disease.