现货Polyethylenimine HCl MAX, Linear, Mw 40,000 (PEI MAX 40000)DESCRIPTIONLinear polyethylenimine HCl MAX, Mw 40,000 (PEI MAX 40000) is a fully hydrolyzed (deacylated), highly water soluble hydrochloride salt form of our Linear Polyethylenimine, Mw 25,000 (PEI 25000, Cat. # 23966). PEI MAX 40000 contains a longer contiguous ethyleneimine segments resulting in more than 11% increase in protonable nitrogens than PEI 25000.PEI MAX 40000 is supplied as a hydrochloride salt for ease of handling and high water solubility. PEI MAX 40000 can be converted into the linear free amine (PEI 22000) form by neutralization with base.See Transporter? 5 Transfection Reagent, Catalog # 26008 for our ready-to-use PEI derivative.CAS#: 9002-98-6, 26913-06-4Molecular Weight: 40,000 (~22,000 free base)Soluble In: Cold and room temperature waterInsoluble in: Common organic solvents (ethanol, acetone, tetrahydrofuran)Appearance: White to off-white free flowing solidReference(s):Baranyi, L. et al. Rapid Generation of Stable Cell Lines Expressing High Levels of Erythropoietin, Factor VIII, and an Antihuman CD20 Antibody Using Lentiviral Vectors. Human Gene Therapy Methods 24, 214–227 (2013). doi:10.1089/hgtb.2013.002Mann JF, McKay PF, Arokiasamy S, Patel RK, Klein K, Shattock RJ. (2013). Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection. J Control Release. 170(3):452-9.Thomas M, Lu JJ, Ge Q, Zhang C, Chen J, Klibanov AM. (2005). Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. Proc Natl Acad Sci U S A. 102(16):5679-84.