抗体名称：UBD抗体,Anti-UBD抗体
背景资料：UBD, also named as FAT10, contains two ubiquitin-like domains. It is a ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. UBD also has important roles in cell mitosis, chromosome instability, apoptosis and immune response. UBD may be a marker for precancerous lesions and may promote cancer progression. It promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). UBD regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. It may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T cell responses. UBD mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). This antibody is a rabbit polyclonal antibody raised against full length UBD of human origin 浓 度： 1mg/1ml
规格：50μg、100μg、150μg 、200μg
宿主：兔源、鼠源、其他
克隆：单克隆、多克隆
适用：人、小鼠、大鼠、鸡、狗、猪、马、羊、猴、牛等
抗体类型：一抗
性 状： 冻干粉或液体
保存建议：提供的UBD抗体,Anti-UBD抗体产品为液体或冻干粉∴，溶解于1x PBS缓冲液(pH 7.3)中。请将其置于 -20°C或更低温度下保存，我们建议分装以避免反复冻融。
产品应用 ：免疫组织化学, 异硫氰☆酸荧光素 , 蛋白质印迹, 石蜡切〗片的免疫组化技术，ELISA 等。
同时提供多种荧光素标记的UBD抗体,Anti-UBD抗体，包括以下荧光素：Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC ，欢迎来电洽谈。
