抗体名称:GPC4抗体,Anti-GPC4抗体
背景资料: Glypicans (GPCs) are a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. In mammals, there are six GPCs (GPC1 to GPC6), all of which have a similar core-protein size of approx. 60 kDa and the clustering of glycosaminoglycan attachment site near the C-terminus. They are tethered to the cell surface by GPI linkages, which can be cleaved by endogenous phospholipases, thus releasing the protein. Human GPC4 is a 556-amino acid protein, and shows 93.5% identity to mouse K-glypican. The gene of GPC4 has been mapped to Xq26, and its mRNA is widely expressed in human tissues, including lung, kidney, heart, placenta, skeletal muscle, and pancreas. GPC4 has also been shown to be present in astrocytes, haematopoietic-progenitor and bone-marrow-stromal cells. Studies suggest that GPC4 is involved in the regulation of Wnt signaling and astrocyte GPC4 plays a role in formation of excitatory synapses. This antobody can recognize both full length (65 kDa) and cleaved (35 kDa) GPC4 as well as GPC6 浓 度: 1mg/1ml
规格:50μg、100μg、150μg 、200μg
宿主:兔源、鼠源、其他
克隆:单克隆、多克隆
适用:人、小鼠、大鼠、鸡、狗、猪、马、羊、猴、牛等
抗体类型:一抗
性 状: 冻干粉或液体
保存建议:提供的GPC4抗体,Anti-GPC4抗体产品为液体或冻干粉,溶解于1x PBS缓冲液(pH 7.3)中。请将其置于▂ -20°C或更低温度下保存,我们建议分装以避免反复冻融。
产品应用 :免疫组织化学, 异硫氰酸荧光素 , 蛋白♀质印迹, 石蜡切片的免疫组化技术,ELISA 等。
同时提︻供多种荧光素标记的GPC4抗体,Anti-GPC4抗体,包括以下荧光素:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC ,欢迎来电洽谈。