抗体名称:ITGA2B抗体;Anti-ITGA2B抗体
背景资料: CD41, also named as ITGA2B CD41B GPIIb GTA and HPA3, is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands and the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. CD41 is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. CD41 chain interacts with the ITGB3 (CD61) to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
浓 度: 1mg/1ml
规格:50μg、100μg、150μg 、200μg
宿主:兔源、鼠源、其他
克隆:单克隆、多克隆
适用:人、小鼠、大鼠、鸡、狗、猪、马、羊、猴、牛等
抗体类型:一抗
性 状: 冻干粉或液体
保存建议:提供的ITGA2B抗体;Anti-ITGA2B抗体产品为液体或▃冻干粉,溶解于1x PBS缓冲液(pH 7.3)中。请将其置于 -20°C或更低温度下保存,我们建议分装以避免反复冻融。
产品应用 :免疫组织化学, 异硫氰ζ 酸荧光素 , 蛋白质印迹, 石蜡切片的免疫组化技术,ELISA 等。
同时提供多种荧光素标记ITGA2B抗体;Anti-ITGA2B抗体,包括以下荧光素:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC ,欢迎来电洽谈。
ITGA2B抗体;Anti-ITGA2B抗体相关抗体:
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TMEFF2增生性息肉蛋白1抗体 Rabbit polyclonal to Cathepsin O - Propeptide domain micrograms Proteins and Peptides Standard
TMED4跨膜蛋白TMED4抗体 Rabbit polyclonal to Cathepsin O - Catalytic domain microlitres Primary antibodies Standard
TM9SF4跨膜蛋白9家族成员4抗体 Rabbit polyclonal to Cathepsin L - Propeptide domain microlitres Primary antibodies Standard
TM9SF1跨膜蛋白超家族9-1抗体 Rabbit polyclonal to Cathepsin L - Catalytic domain microlitres Primary antibodies Standard
TM7SF2/DHCR14A脱氢胆固醇还原酶14抗体 Rabbit polyclonal to Cathepsin L microlitres Primary antibodies Standard
TM4SF3跨膜蛋白4超家族成员3抗体 Rabbit polyclonal to Cathepsin L microlitres Primary antibodies Standard
TM4SF3TM4SF3蛋白抗体 Rabbit polyclonal to Cathepsin L microlitres Primary antibodies Standard
TLX3T细胞白血病同源盒蛋白3抗体 Rabbit polyclonal to Cathepsin K - Catalytic domain micrograms Proteins and Peptides Standard
ITGA2B抗体;Anti-ITGA2B抗体知识拓展》》》抗原修复的临床应用:
上个世纪九十年代早期,随着抗原修复技术的发展,免疫组化应用在常规处理火胶棉包埋的人类颞骨∞上,从分子水平上了解人类发病机理和病理生理学,创立了一个新的领域[13]。使用抗原修复方法,在常规处理石蜡切片上评估IC5和ID15单克隆抗体的免疫组化染色[14]。 Charalambous. C等人 [15]强烈推荐MW-AR-IHC方法检测R-S细胞的CD30。抗原修复技术成功应用于原位杂交[16]。利用加热抗原修复-免疫组化技术,在福尔马林固定、石蜡组织切片上用抗毒素#4350检测nestin[17]。采用抗复技术,在人类上皮、神经、神经内分泌组织中免疫组化定位DCC蛋白[18]。抗原修复-免疫组化已广泛应用于¤临床的研究中。