抗体名称:NOB1抗体,Anti-NOB1抗体
背景资料: NOB1 was first identified in yeast as an essential gene encoding the Nin one binding protein, which is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA. In addition, NOB1 is a crucial molecule in the maturation of the 20S proteasome and protein degradation. It serves as a chaperone to join the 20S proteasome with the 19S regulatory particle in the nucleus and facilitates the maturation of the 20S proteasome. Recently NOB1 has been reported to be overexpressed in several types of cancer, suggesting its involvement in the tumorigenesis. 浓 度: 1mg/1ml
规格:50μg、100μg、150μg 、200μg
宿主:兔源、鼠源、其他
克隆:单克隆、多克隆
适用:人、小鼠、大鼠、鸡、狗、猪、马、羊、猴、牛等
抗体类型:一抗
性 状: 冻干粉或液体
保存建议:提供的NOB1抗体,Anti-NOB1抗体产品为液体或冻干粉,溶解于1x PBS缓冲液(pH 7.3)中。请将其置于 -20°C或更低温度下保存,我们建议分⌒ 装以避免反复冻融。
产品应用 :免疫组织化学, 异硫氰酸荧光素 , 蛋白质印迹, 石蜡切片的免疫组化技术,ELISA 等。
同时提供多种荧光素标记的NOB1抗体,Anti-NOB1抗体,包括以下荧光素:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC ,欢迎来电洽谈。
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人舌鳞癌细胞 Rabbit polyclonal to Gliadin (HRP) micrograms Proteins and Peptides Standard
人舌鳞癌细胞 Rabbit polyclonal to Gliadin micrograms Proteins and Peptides Standard
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人舌癌细胞系 Rabbit polyclonal to Gli3 micrograms Lysates Standard
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NOB1抗体,Anti-NOB1抗体知识拓展》》》抗原修复的临床应用:
上个世纪九十年代早期,随着抗原修复技术的发展,免疫组化应用在常规处理火胶棉包埋的人类颞骨上,从分子水平上了解人类发病机理和病理生理学,创立了一个新的领域[13]。使用抗原修复方法,在常规处理石蜡切片♀上评估IC5和ID15单克隆抗体的免疫组化染色[14]。 Charalambous. C等人 [15]强烈推荐MW-AR-IHC方法检测R-S细胞的CD30。抗原修复技术成功应用于原位杂交[16]。利用加热抗原︼修复-免疫组化技术,在福尔马林固定、石蜡组织切片上用抗毒素#4350检测nestin[17]。采用抗复技术,在人类上皮、神经、神经内分泌组织中免疫组化定位DCC蛋白[18]。抗原修复-免疫组化已广泛应用于临床的研究中。